NSF to Invest $100 Million in AI-Programmable Cloud Laboratories
Technology journalist focusing on innovation, startups, and digital transformation

The U.S. National Science Foundation (NSF) has announced a substantial new funding opportunity aimed at transforming scientific research across the United States. With an investment of up to $100 million, the NSF plans to establish a network of 'programmable cloud laboratories' designed to accelerate scientific discovery and innovation through the integration of cutting-edge artificial intelligence (AI) technologies.
The NSF's new initiative, the Programmable Cloud Laboratories (PCL) Test Bed, seeks to create a national infrastructure where AI-enabled laboratories can be accessed remotely. This ambitious project will allow researchers to program custom AI-enabled workflows, facilitating more efficient and precise scientific and engineering experiments. The initial focus of these laboratories will be on biotechnology and materials science, two fields poised to reap significant benefits from AI-driven experimentation. This move is part of the wider White House AI Action Plan, emphasizing the importance of automated laboratory infrastructure in advancing scientific research.
Erwin Gianchandani, NSF Assistant Director for Technology, Innovation and Partnerships, highlighted the transformative potential of the PCL initiative. By leveraging AI at every stage of laboratory experiments—pre-experiment, during the experiment, and post-experiment—researchers can significantly enhance the accuracy, efficiency, and overall impact of their work. For instance, AI can assist in designing the best experimental setups, predicting outcomes, and automating data collection and analysis. This reduces the reliance on trial-and-error methods, saving valuable time and resources.
In addition to transforming research methodologies, the PCL initiative is set to play a pivotal role in education and training. By integrating advanced AI-enabled laboratories into classroom settings, NSF aims to equip the next generation of scientists and engineers with the skills necessary to harness the power of AI in their future careers. The program anticipates making up to six awards, each up to $5 million per year for four years, to educational institutions, nonprofit organizations, and for-profit entities.
This initiative is part of a broader effort by the NSF to develop multiple test platforms that enable researchers to refine groundbreaking technologies in secure, real-world settings. In summer 2024, the NSF launched the National Quantum Virtual Laboratory and Biofoundries initiatives, aimed at advancing modern biology and biotechnology. The new AI-Ready Test Beds initiative further underscores the agency's commitment to fostering innovation and maintaining U.S. leadership in science and technology.
As the science and technology landscape continues to evolve rapidly, initiatives like the PCL Test Bed represent crucial steps towards addressing the complex challenges faced by researchers today. By investing in AI-enabled infrastructure, the NSF is not only enhancing the capabilities of U.S. laboratories but also ensuring that American researchers remain at the forefront of global scientific innovation. This initiative promises to unlock new possibilities in data generation, interpretation, and application across various scientific domains.
About Emma Thompson
Technology journalist focusing on innovation, startups, and digital transformation